InCatT B.V. (short for Innovative Catalyst Technologies) is a privately held company founded in 2009 based in The Netherlands. InCatT provides contract research for transition metal catalysed reactions with a proven track-record in Pharma industry, Flavor & Fragrance industry, oil industry, coatings industry and for companies active in the bio-based materials conversion.
InCatT has the experience, knowledge and infrastructure for high throughput catalyst screening. Employing robotics, InCatT can perform very large number reactions (up to 96 reactions per day) in parallel to rapidly screen chemical reaction spaces (and thus finding new catalyst hits that otherwise would require a lot of time and resources). The catalyst systems identified are then investigated in full detail using an advanced SPR16 AMTEC system. This system can perform 16 reactions parallel and under strict reaction control record the gas-uptake curves providing the full kinetic data in an overnight experiment. The kinetics of the catalyst system is used to identify the window of operation, catalyst stability, substrate and or product inhibition.
In the past we have worked on various catalytic conversions such as:
• (Asymmetric) hydrogenation
• (Asymmetric) hydroformylation
• Palladium cross-coupling chemistry
• Propene dimerization chemistry at cryogenic temperatures
In addition to the catalyst screening, InCatT also provides the option to scale up the catalytic reaction to 20 Litres which can handle high pressure reactions up to 80 bar (and between -50 and 150 °C). With extra services we can our customers with the first kilograms of product for further study and development.
For a number of catalytic conversions, InCatT has developed its own proprietary catalyst systems such as the world famous METAMorphos ligands which show unprecedented activities / selectivities in these catalytic reactions. InCatT is considered an expert in innovative catalyst research which is proven by the publications that have appeared in peer-reviewed journals.